Rossmann-toolbox: a deep learning-based protocol for the prediction and design of cofactor specificity in Rossmann fold proteins

The Rossmann fold enzymes are involved in essential biochemical pathways such as nucleotide and amino acid metabolism. Their functioning relies on interaction with cofactors, small nucleoside-based compounds specifically recognized by a conserved βαβ motif shared by all Rossmann fold proteins. While...

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Detalles Bibliográficos
Autores principales: Kamiński, Kamil, Ludwiczak, Jan, Jasiński, Maciej, Bukala, Adriana, Madaj, Rafal, Szczepaniak, Krzysztof, Dunin-Horkawicz, Stanisław
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Problem Solving Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8769691/
https://www.ncbi.nlm.nih.gov/pubmed/34571541
http://dx.doi.org/10.1093/bib/bbab371

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8769691/
https://www.ncbi.nlm.nih.gov/pubmed/34571541
http://dx.doi.org/10.1093/bib/bbab371

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