Cargando…
Rossmann-toolbox: a deep learning-based protocol for the prediction and design of cofactor specificity in Rossmann fold proteins
The Rossmann fold enzymes are involved in essential biochemical pathways such as nucleotide and amino acid metabolism. Their functioning relies on interaction with cofactors, small nucleoside-based compounds specifically recognized by a conserved βαβ motif shared by all Rossmann fold proteins. While...
Autores principales: | Kamiński, Kamil, Ludwiczak, Jan, Jasiński, Maciej, Bukala, Adriana, Madaj, Rafal, Szczepaniak, Krzysztof, Dunin-Horkawicz, Stanisław |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8769691/ https://www.ncbi.nlm.nih.gov/pubmed/34571541 http://dx.doi.org/10.1093/bib/bbab371 |
Ejemplares similares
-
Insertions and deletions mediated functional divergence of Rossmann fold enzymes
por: Toledo-Patiño, Saacnicteh, et al.
Publicado: (2022) -
An Ancient Fingerprint Indicates the Common Ancestry of Rossmann-Fold Enzymes Utilizing Different Ribose-Based Cofactors
por: Laurino, Paola, et al.
Publicado: (2016) -
Functional and evolutionary analysis of viral proteins containing a Rossmann‐like fold
por: Medvedev, Kirill E., et al.
Publicado: (2018) -
S-adenosyl-l-homocysteine Hydrolase: A Structural Perspective on the Enzyme with Two Rossmann-Fold Domains
por: Brzezinski, Krzysztof
Publicado: (2020) -
A library of coiled-coil domains: from regular bundles to peculiar twists
por: Szczepaniak, Krzysztof, et al.
Publicado: (2020)