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Differential effects of vascular endothelial growth factor on glycocalyx of endothelial and tumor cells and potential targets for tumor metastasis

On the surface of every mammalian cell, there is a matrix-like glycocalyx (GCX) consisting of proteoglycans and glycosaminoglycans (GAGs). Disruption of endothelial cell (EC) GCX by a vascular endothelial growth factor (VEGF, VEGF-A(165)), a tumor secretion, was found to be an early event in tumor c...

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Detalles Bibliográficos
Autores principales: Xia, Yifan, Li, Yunfei, Fu, Bingmei M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AIP Publishing LLC 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8769769/
https://www.ncbi.nlm.nih.gov/pubmed/35071967
http://dx.doi.org/10.1063/5.0064381