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Low maternal vitamin A intake increases the incidence of teratogen induced congenital diaphragmatic hernia in mice

BACKGROUND: Congenital diaphragmatic hernia (CDH) is a severe birth defect associated with high perinatal mortality and long-term morbidity. The etiology of CDH is poorly understood although abnormal retinoid signaling has been proposed to contribute to abnormal diaphragm development. Existing epide...

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Detalles Bibliográficos
Autores principales: Rocke, Ayanna W., Clarke, Tianna G., Dalmer, Timothy R. A., McCluskey, Sydney A., Rivas, Juan F. Garcia, Clugston, Robin D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8770141/
https://www.ncbi.nlm.nih.gov/pubmed/33654278
http://dx.doi.org/10.1038/s41390-021-01409-6