Genome surveillance by HUSH-mediated silencing of intronless mobile elements

All life forms defend their genome against DNA invasion. Eukaryotic cells recognize incoming DNA and limit its transcription through repressive chromatin modifications. The human silencing hub (HUSH) complex transcriptionally represses long interspersed element-1 retrotransposons (L1s) and retroviru...

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Detalles Bibliográficos
Autores principales: Seczynska, Marta, Bloor, Stuart, Cuesta, Sergio Martinez, Lehner, Paul J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8770142/
https://www.ncbi.nlm.nih.gov/pubmed/34794168
http://dx.doi.org/10.1038/s41586-021-04228-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8770142/
https://www.ncbi.nlm.nih.gov/pubmed/34794168
http://dx.doi.org/10.1038/s41586-021-04228-1

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