SNP and Haplotype Regional Heritability Mapping (SNHap-RHM): Joint Mapping of Common and Rare Variation Affecting Complex Traits

We describe a genome-wide analytical approach, SNP and Haplotype Regional Heritability Mapping (SNHap-RHM), that provides regional estimates of the heritability across locally defined regions in the genome. This approach utilises relationship matrices that are based on sharing of SNP and haplotype a...

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Detalles Bibliográficos
Autores principales: Oppong, Richard F., Boutin, Thibaud, Campbell, Archie, McIntosh, Andrew M., Porteous, David, Hayward, Caroline, Haley, Chris S., Navarro, Pau, Knott, Sara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8770330/
https://www.ncbi.nlm.nih.gov/pubmed/35069690
http://dx.doi.org/10.3389/fgene.2021.791712

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8770330/
https://www.ncbi.nlm.nih.gov/pubmed/35069690
http://dx.doi.org/10.3389/fgene.2021.791712

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