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SNP and Haplotype Regional Heritability Mapping (SNHap-RHM): Joint Mapping of Common and Rare Variation Affecting Complex Traits

We describe a genome-wide analytical approach, SNP and Haplotype Regional Heritability Mapping (SNHap-RHM), that provides regional estimates of the heritability across locally defined regions in the genome. This approach utilises relationship matrices that are based on sharing of SNP and haplotype a...

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Detalles Bibliográficos
Autores principales:	Oppong, Richard F., Boutin, Thibaud, Campbell, Archie, McIntosh, Andrew M., Porteous, David, Hayward, Caroline, Haley, Chris S., Navarro, Pau, Knott, Sara
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8770330/ https://www.ncbi.nlm.nih.gov/pubmed/35069690 http://dx.doi.org/10.3389/fgene.2021.791712

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