Matrix metalloproteinase-7 induces E-cadherin cleavage in acid-exposed primary human pharyngeal epithelial cells via the ROS/ERK/c-Jun pathway

ABSTRACT: Laryngopharyngeal reflux disease (LPRD) is caused by pharyngeal mucosal damage due to the reflux of gastric contents, including acid, pepsin, and bile juice. Our previous study has demonstrated that LPRD is associated with the cleavage of E-cadherin, which is facilitated by the acid-activa...

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Detalles Bibliográficos
Autores principales: Im, Nu-Ri, Kim, Byoungjae, Jung, Kwang-Yoon, Baek, Seung-Kuk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8770433/
https://www.ncbi.nlm.nih.gov/pubmed/34973082
http://dx.doi.org/10.1007/s00109-021-02166-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8770433/
https://www.ncbi.nlm.nih.gov/pubmed/34973082
http://dx.doi.org/10.1007/s00109-021-02166-z

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