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Matrix metalloproteinase-7 induces E-cadherin cleavage in acid-exposed primary human pharyngeal epithelial cells via the ROS/ERK/c-Jun pathway
ABSTRACT: Laryngopharyngeal reflux disease (LPRD) is caused by pharyngeal mucosal damage due to the reflux of gastric contents, including acid, pepsin, and bile juice. Our previous study has demonstrated that LPRD is associated with the cleavage of E-cadherin, which is facilitated by the acid-activa...
Autores principales: | Im, Nu-Ri, Kim, Byoungjae, Jung, Kwang-Yoon, Baek, Seung-Kuk |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8770433/ https://www.ncbi.nlm.nih.gov/pubmed/34973082 http://dx.doi.org/10.1007/s00109-021-02166-z |
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