Protease-activated receptor 2 activation induces behavioural changes associated with depression-like behaviour through microglial-independent modulation of inflammatory cytokines

RATIONALE: Major depressive disorder (MDD) is a leading cause of disability worldwide but currently prescribed treatments do not adequately ameliorate the disorder in a significant portion of patients. Hence, a better appreciation of its aetiology may lead to the development of novel therapies. OBJE...

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Detalles Bibliográficos
Autores principales: Moudio, Serge, Willis, Ashleigh, Pytka, Karolina, Abulkassim, Roua, Brett, Ros R., Webster, Jack F., Wozny, Christian, Barbour, Mark, Jiang, Hui-Rong, Watson, David G., van Kralingen, Josie C., MacKenzie, Scott M., Daniels, Michael, McColl, Barry W., Sossick, Sandra, Nuthall, Hugh N., Bushell, Trevor J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8770450/
https://www.ncbi.nlm.nih.gov/pubmed/34888704
http://dx.doi.org/10.1007/s00213-021-06040-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8770450/
https://www.ncbi.nlm.nih.gov/pubmed/34888704
http://dx.doi.org/10.1007/s00213-021-06040-1

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