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Protease-activated receptor 2 activation induces behavioural changes associated with depression-like behaviour through microglial-independent modulation of inflammatory cytokines
RATIONALE: Major depressive disorder (MDD) is a leading cause of disability worldwide but currently prescribed treatments do not adequately ameliorate the disorder in a significant portion of patients. Hence, a better appreciation of its aetiology may lead to the development of novel therapies. OBJE...
Autores principales: | Moudio, Serge, Willis, Ashleigh, Pytka, Karolina, Abulkassim, Roua, Brett, Ros R., Webster, Jack F., Wozny, Christian, Barbour, Mark, Jiang, Hui-Rong, Watson, David G., van Kralingen, Josie C., MacKenzie, Scott M., Daniels, Michael, McColl, Barry W., Sossick, Sandra, Nuthall, Hugh N., Bushell, Trevor J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8770450/ https://www.ncbi.nlm.nih.gov/pubmed/34888704 http://dx.doi.org/10.1007/s00213-021-06040-1 |
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