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Dexmedetomidine promotes apoptosis and suppresses proliferation of hepatocellular carcinoma cells via microRNA-130a/EGR1 axis

Accumulating evidence has revealed the role of microRNAs (miRs) in hepatocellular carcinoma (HCC). Dexmedetomidine, a highly selective α(2)-adrenergic agonist, is widely used in perioperative settings for analgesia and sedation. Herein, we aimed to determine whether dexmedetomidine might directly re...

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Detalles Bibliográficos
Autores principales: Zhou, Lei, Li, Juanni, Liu, Xing, Tang, Yongzhong, Li, Tunliang, Deng, Huiyin, Chen, Jia, Yin, Xinlin, Hu, Kuan, Ouyang, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8770558/
https://www.ncbi.nlm.nih.gov/pubmed/35046398
http://dx.doi.org/10.1038/s41420-021-00805-5