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Experimental identification of aminomethanol (NH(2)CH(2)OH)—the key intermediate in the Strecker Synthesis

The Strecker Synthesis of (a)chiral α-amino acids from simple organic compounds, such as ammonia (NH(3)), aldehydes (RCHO), and hydrogen cyanide (HCN) has been recognized as a viable route to amino acids on primordial earth. However, preparation and isolation of the simplest hemiaminal intermediate...

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Detalles Bibliográficos
Autores principales: Singh, Santosh K., Zhu, Cheng, La Jeunesse, Jesse, Fortenberry, Ryan C., Kaiser, Ralf I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8770675/
https://www.ncbi.nlm.nih.gov/pubmed/35046418
http://dx.doi.org/10.1038/s41467-022-27963-z