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Trehangelins ameliorate inflammation-induced skin senescence by suppressing the epidermal YAP-CCN1 axis

Trehangelins (THG) are newly identified trehalose compounds derived from broth cultures of an endophytic actinomycete, Polymorphospora rubra. THG are known to suppress Cellular Communication Network factor 1 (CCN1), which regulates collagen homeostasis in the dermis. Although the physical properties...

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Detalles Bibliográficos
Autores principales: Yokota, Mami, Kamiya, Yoshiyuki, Suzuki, Tamie, Ishikawa, Shinsuke, Takeda, Akira, Kondo, Shinya, Tohgasaki, Takeshi, Nakashima, Takuji, Takahashi, Yoko, Ōmura, Satoshi, Sakurai, Tetsuhito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8770704/
https://www.ncbi.nlm.nih.gov/pubmed/35046484
http://dx.doi.org/10.1038/s41598-022-04924-6