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Trehangelins ameliorate inflammation-induced skin senescence by suppressing the epidermal YAP-CCN1 axis
Trehangelins (THG) are newly identified trehalose compounds derived from broth cultures of an endophytic actinomycete, Polymorphospora rubra. THG are known to suppress Cellular Communication Network factor 1 (CCN1), which regulates collagen homeostasis in the dermis. Although the physical properties...
Autores principales: | Yokota, Mami, Kamiya, Yoshiyuki, Suzuki, Tamie, Ishikawa, Shinsuke, Takeda, Akira, Kondo, Shinya, Tohgasaki, Takeshi, Nakashima, Takuji, Takahashi, Yoko, Ōmura, Satoshi, Sakurai, Tetsuhito |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8770704/ https://www.ncbi.nlm.nih.gov/pubmed/35046484 http://dx.doi.org/10.1038/s41598-022-04924-6 |
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