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Worse Physical Disability Is Associated With the Expression of PD-1 on Inflammatory T-Cells in Multiple Sclerosis Patients With Older Appearing Brains

Background: Magnetic Resonance Imaging (MRI) analysis method “brain-age” paradigm could offer an intuitive prognostic metric (brain-predicted age difference: brain-PAD) for disability in Multiple Sclerosis (MS), reflecting structural brain health adjusted for aging. Equally, cellular senescence has...

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Detalles Bibliográficos
Autores principales: Jacobs, Sophie A. H., Muraro, Paolo A., Cencioni, Maria T., Knowles, Sarah, Cole, James H., Nicholas, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8770747/
https://www.ncbi.nlm.nih.gov/pubmed/35069428
http://dx.doi.org/10.3389/fneur.2021.801097