Cargando…

Restoring p53 Function in Head and Neck Squamous Cell Carcinoma to Improve Treatments

TP53 mutation is one of the most frequent genetic alterations in head and neck squamous cell carcinoma (HNSCC) and results in an accumulation of p53 protein in tumor cells. This makes p53 an attractive target to improve HNSCC therapy by restoring the tumor suppressor activity of this protein. Therap...

Descripción completa

Detalles Bibliográficos
Autores principales: de Bakker, Tycho, Journe, Fabrice, Descamps, Géraldine, Saussez, Sven, Dragan, Tatiana, Ghanem, Ghanem, Krayem, Mohammad, Van Gestel, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8770810/
https://www.ncbi.nlm.nih.gov/pubmed/35071005
http://dx.doi.org/10.3389/fonc.2021.799993