Cargando…
Restoring p53 Function in Head and Neck Squamous Cell Carcinoma to Improve Treatments
TP53 mutation is one of the most frequent genetic alterations in head and neck squamous cell carcinoma (HNSCC) and results in an accumulation of p53 protein in tumor cells. This makes p53 an attractive target to improve HNSCC therapy by restoring the tumor suppressor activity of this protein. Therap...
Autores principales: | de Bakker, Tycho, Journe, Fabrice, Descamps, Géraldine, Saussez, Sven, Dragan, Tatiana, Ghanem, Ghanem, Krayem, Mohammad, Van Gestel, Dirk |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8770810/ https://www.ncbi.nlm.nih.gov/pubmed/35071005 http://dx.doi.org/10.3389/fonc.2021.799993 |
Ejemplares similares
-
Galectins and Carcinogenesis: Their Role in Head and Neck Carcinomas and Thyroid Carcinomas
por: Kindt, Nadège, et al.
Publicado: (2017) -
PRIMA-1 and PRIMA-1(Met) (APR-246): From Mutant/Wild Type p53 Reactivation to Unexpected Mechanisms Underlying Their Potent Anti-Tumor Effect in Combinatorial Therapies
por: Perdrix, Anne, et al.
Publicado: (2017) -
Radiotherapy Quality Assurance for Head and Neck Squamous Cell Carcinoma
por: Van Gestel, Dirk, et al.
Publicado: (2020) -
HPV Involvement in the Tumor Microenvironment and Immune Treatment in Head and Neck Squamous Cell Carcinomas
por: Lechien, Jérôme R., et al.
Publicado: (2020) -
Dealing with Macrophage Plasticity to Address Therapeutic Challenges in Head and Neck Cancers
por: Furgiuele, Sonia, et al.
Publicado: (2022)