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The Predictive Value of MAP2K1/2 Mutations on Efficiency of Immunotherapy in Melanoma

BACKGROUND: MAP2K1/2 genes are mutated in approximately 8% of melanoma patients; however, the impact of MAP2K1/2 gene alterations on the efficiency of immunotherapy has not been clarified. This study focused on the correlation between MAP2K1/2 gene mutations and the treatment response. METHODS: Six...

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Detalles Bibliográficos
Autores principales: Ye, Ting, Zhang, Jie-Ying, Liu, Xin-Yi, Zhou, Yu-Han, Yuan, Si-Yue, Yang, Meng-Mei, Xie, Wen-Zhuan, Gao, Chan, Chen, Yao-Xu, Huang, Meng-Li, Ye, Cheng-Zhi, Chen, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8770828/
https://www.ncbi.nlm.nih.gov/pubmed/35069558
http://dx.doi.org/10.3389/fimmu.2021.785526