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SPAG6基因沉默和地西他滨对SKM-1细胞凋亡和PTEN甲基化的影响

OBJECTIVE: To investigate the effects of SPAG6 silencing and decitabine on apoptosis and phosphatase and tensin homolog (PTEN) methylation in SKM-1 cells in vitro and in vivo. METHODS: SKM-1 cells were transfected with a lentiviral vector to silence the expression of SPAG6. Cell survival rate was de...

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Detalles Bibliográficos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Editorial office of Chinese Journal of Hematology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8770872/
https://www.ncbi.nlm.nih.gov/pubmed/35045671
http://dx.doi.org/10.3760/cma.j.issn.0253-2727.2021.12.007