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siRNA对血红蛋白H病红系细胞β珠蛋白的调控作用
OBJECTIVE: To investigate the regulatory effect of targeted siRNA on β-globin in erythroid cells cultured by targeted differentiation in vitro and provide new theoretical support for gene therapy for hemoglobin H (HbH) disease. METHODS: Based on the β-globin gene expression results, the optimal siRN...
| Formato: | Online Artículo Texto |
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| Lenguaje: | English |
| Publicado: |
Editorial office of Chinese Journal of Hematology
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8770884/ https://www.ncbi.nlm.nih.gov/pubmed/35045673 http://dx.doi.org/10.3760/cma.j.issn.0253-2727.2021.12.009 |