Structure and Fc-Effector Function of Rhesusized Variants of Human Anti-HIV-1 IgG1s

Passive transfer of monoclonal antibodies (mAbs) of human origin into Non-Human Primates (NHPs), especially those which function predominantly by a Fc-effector mechanism, requires an a priori preparation step, in which the human mAb is reengineered to an equivalent NHP IgG subclass. This can be achi...

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Detalles Bibliográficos
Autores principales: Tolbert, William D., Nguyen, Dung N., Tuyishime, Marina, Crowley, Andrew R., Chen, Yaozong, Jha, Shalini, Goodman, Derrick, Bekker, Valerie, Mudrak, Sarah V., DeVico, Anthony L., Lewis, George K., Theis, James F., Pinter, Abraham, Moody, M. Anthony, Easterhoff, David, Wiehe, Kevin, Pollara, Justin, Saunders, Kevin O., Tomaras, Georgia D., Ackerman, Margaret, Ferrari, Guido, Pazgier, Marzena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8770954/
https://www.ncbi.nlm.nih.gov/pubmed/35069563
http://dx.doi.org/10.3389/fimmu.2021.787603

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8770954/
https://www.ncbi.nlm.nih.gov/pubmed/35069563
http://dx.doi.org/10.3389/fimmu.2021.787603

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