NFATc1/αA and Blimp-1 Support the Follicular and Effector Phenotype of Tregs

CD4(+)CXCR5(+)Foxp3(+) T-follicular regulatory (T(FR)) cells control the germinal center responses. Like T-follicular helper cells, they express high levels of Nuclear Factor of Activated T-cells c1 , predominantly its short isoform NFATc1/αA. Ablation of NFATc1 in Tregs prevents upregulation of CXC...

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Detalles Bibliográficos
Autores principales: Koenig, Anika, Vaeth, Martin, Xiao, Yin, Chiarolla, Cristina M., Erapaneedi, Raghu, Klein, Matthias, Dietz, Lena, Hundhausen, Nadine, Majumder, Snigdha, Schuessler, Felix, Bopp, Tobias, Klein-Hessling, Stefan, Rosenwald, Andreas, Berberich, Ingolf, Berberich-Siebelt, Friederike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8770984/
https://www.ncbi.nlm.nih.gov/pubmed/35069572
http://dx.doi.org/10.3389/fimmu.2021.791100

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8770984/
https://www.ncbi.nlm.nih.gov/pubmed/35069572
http://dx.doi.org/10.3389/fimmu.2021.791100

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