Critical role of mitochondrial aldehyde dehydrogenase 2 in acrolein sequestering in rat spinal cord injury

Lipid peroxidation-derived aldehydes, such as acrolein, the most reactive aldehyde, have emerged as key culprits in sustaining post-spinal cord injury (SCI) secondary pathologies leading to functional loss. Strong evidence suggests that mitochondrial aldehyde dehydrogenase-2 (ALDH2), a key oxidoredu...

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Detalles Bibliográficos
Autores principales: Herr, Seth A., Shi, Liangqin, Gianaris, Thomas, Jiao, Yucheng, Sun, Siyuan, Race, Nick, Shapiro, Scott, Shi, Riyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8771087/
https://www.ncbi.nlm.nih.gov/pubmed/34916435
http://dx.doi.org/10.4103/1673-5374.330613

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8771087/
https://www.ncbi.nlm.nih.gov/pubmed/34916435
http://dx.doi.org/10.4103/1673-5374.330613

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