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Critical role of mitochondrial aldehyde dehydrogenase 2 in acrolein sequestering in rat spinal cord injury
Lipid peroxidation-derived aldehydes, such as acrolein, the most reactive aldehyde, have emerged as key culprits in sustaining post-spinal cord injury (SCI) secondary pathologies leading to functional loss. Strong evidence suggests that mitochondrial aldehyde dehydrogenase-2 (ALDH2), a key oxidoredu...
Autores principales: | Herr, Seth A., Shi, Liangqin, Gianaris, Thomas, Jiao, Yucheng, Sun, Siyuan, Race, Nick, Shapiro, Scott, Shi, Riyi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8771087/ https://www.ncbi.nlm.nih.gov/pubmed/34916435 http://dx.doi.org/10.4103/1673-5374.330613 |
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