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Phosphoinositide-3-kinase regulatory subunit 4 participates in the occurrence and development of amyotrophic lateral sclerosis by regulating autophagy

The development of amyotrophic lateral sclerosis (ALS) may be related to the abnormal alterations of multiple proteins. Our previous study revealed that the expression of phosphoinositide-3-kinase regulatory subunit 4 (PIK3R4) was decreased in ALS. However, the role of PIK3R4 in ALS pathogenesis rem...

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Detalles Bibliográficos
Autores principales: Liu, Yue, Wei, Cai-Hui, Li, Cheng, Chen, Wen-Zhi, Zhu, Yu, Xu, Ren-Shi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8771104/
https://www.ncbi.nlm.nih.gov/pubmed/34916448
http://dx.doi.org/10.4103/1673-5374.330621