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theLiTE™: A Screening Platform to Identify Compounds that Reinforce Tight Junctions
Tight junctions (TJ) are formed by transmembrane and intracellular proteins that seal the intercellular space and control selective permeability of epithelia. Integrity of the epithelial barrier is central to tissue homeostasis and barrier dysfunction has been linked to many pathological conditions....
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8771259/ https://www.ncbi.nlm.nih.gov/pubmed/35069190 http://dx.doi.org/10.3389/fphar.2021.752787 |