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theLiTE™: A Screening Platform to Identify Compounds that Reinforce Tight Junctions

Tight junctions (TJ) are formed by transmembrane and intracellular proteins that seal the intercellular space and control selective permeability of epithelia. Integrity of the epithelial barrier is central to tissue homeostasis and barrier dysfunction has been linked to many pathological conditions....

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Detalles Bibliográficos
Autores principales: Gomes, Teresa Lopes, de Oliveira-Marques, Virgínia, Hampson, Richard John, Jacinto, António, de Moraes, Luciana Vieira, Martinho, Rui Gonçalo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8771259/
https://www.ncbi.nlm.nih.gov/pubmed/35069190
http://dx.doi.org/10.3389/fphar.2021.752787