Hedgehog signaling is controlled by Rac1 activity

Rationale: The nuclear translocation of transcriptional factor Gli is indispensable for Hedgehog (Hh) signaling activation, whose deregulation causes cancer progressions; however, the mechanisms governing Gli nuclear translocation are poorly understood. Here, we report that the Gli translocation in...

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Detalles Bibliográficos
Autores principales: Tang, Chao, Wu, Ximei, Ren, Qianlei, Yao, Minli, Xu, Shouying, Yan, Ziyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8771550/
https://www.ncbi.nlm.nih.gov/pubmed/35154488
http://dx.doi.org/10.7150/thno.67702

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8771550/
https://www.ncbi.nlm.nih.gov/pubmed/35154488
http://dx.doi.org/10.7150/thno.67702

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