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α-Catulin promotes cancer stemness by antagonizing WWP1-mediated KLF5 degradation in lung cancer

Background: The cytoskeletal linker protein α-Catulin has been shown to be important for tumor progression in various cancers. However, its role in the regulation of cancer stemness remains unclear. Methods: Phenotypic effects of α-Catulin on the cancer stem cell (CSC)-like properties and metastasis...

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Detalles Bibliográficos
Autores principales: Tung, Chia-Hao, Huang, Meng-Fan, Liang, Chen-Hsien, Wu, Yi-Ying, Wu, Jia-En, Hsu, Cheng-Lung, Chen, Yuh-Ling, Hong, Tse-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8771551/
https://www.ncbi.nlm.nih.gov/pubmed/35154481
http://dx.doi.org/10.7150/thno.63627