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Overcoming resistance to EGFR monotherapy in HNSCC by identification and inhibition of individualized cancer processes

Therapeutic strategies for advanced head and neck squamous carcinoma (HNSCC) consist of multimodal treatment, including Epidermal Growth Factor Receptor (EGFR) inhibition, immune-checkpoint inhibition, and radio (chemo) therapy. Although over 90% of HNSCC tumors overexpress EGFR, attempts to replace...

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Detalles Bibliográficos
Autores principales: Jubran, Maria R., Vilenski, Daniela, Flashner-Abramson, Efrat, Shnaider, Efraim, Vasudevan, Swetha, Rubinstein, Ariel M., Meirovitz, Amichay, Sharon, Shay, Polak, David, Kravchenko-Balasha, Nataly
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8771558/
https://www.ncbi.nlm.nih.gov/pubmed/35154483
http://dx.doi.org/10.7150/thno.64347