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Mitochondrion-targeted supramolecular “nano-boat” simultaneously inhibiting dual energy metabolism for tumor selective and synergistic chemo-radiotherapy

Rationale: Tumor energy metabolism has been a well-appreciated target of cancer therapy; however, the metabolism change of cancer cells between oxidative phosphorylation and glycolysis poses a challenge to the above. In this study, we constructed an innovative mitochondrion-targeted supramolecular “...

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Detalles Bibliográficos
Autores principales: Gao, Jie, Wang, Zhilong, Guo, Qingxiang, Tang, Huan, Wang, Zhongyan, Yang, Cuihong, Fan, Huirong, Zhang, Wenxue, Ren, Chunhua, Liu, Jianfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8771563/
https://www.ncbi.nlm.nih.gov/pubmed/35154487
http://dx.doi.org/10.7150/thno.67543