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Strainline: full-length de novo viral haplotype reconstruction from noisy long reads

Haplotype-resolved de novo assembly of highly diverse virus genomes is critical in prevention, control and treatment of viral diseases. Current methods either can handle only relatively accurate short read data, or collapse haplotype-specific variations into consensus sequence. Here, we present Stra...

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Detalles Bibliográficos
Autores principales: Luo, Xiao, Kang, Xiongbin, Schönhuth, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8771625/
https://www.ncbi.nlm.nih.gov/pubmed/35057847
http://dx.doi.org/10.1186/s13059-021-02587-6