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Quercetin induces tongue squamous cell carcinoma cell apoptosis via the JNK activation-regulated ERK/GSK-3α/β-mediated mitochondria-dependent apoptotic signaling pathway

Tongue squamous cell carcinoma (SCC) is a most common type of oral cancer. Due to its highly invasive nature and poor survival rate, the development of effective pharmacological therapeutic agents is urgently required. Quercetin (3,3′,4′,5,7-pentahydroxyflavone) is a polyphenolic flavonoid found in...

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Detalles Bibliográficos
Autores principales: Huang, Chun-Fa, Liu, Shing-Hwa, Ho, Tsung-Jung, Lee, Kuan-I, Fang, Kai-Min, Lo, Wu-Chia, Liu, Jui-Ming, Wu, Chin-Ching, Su, Chin-Chuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8771640/
https://www.ncbi.nlm.nih.gov/pubmed/35111247
http://dx.doi.org/10.3892/ol.2022.13198