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Quercetin induces tongue squamous cell carcinoma cell apoptosis via the JNK activation-regulated ERK/GSK-3α/β-mediated mitochondria-dependent apoptotic signaling pathway
Tongue squamous cell carcinoma (SCC) is a most common type of oral cancer. Due to its highly invasive nature and poor survival rate, the development of effective pharmacological therapeutic agents is urgently required. Quercetin (3,3′,4′,5,7-pentahydroxyflavone) is a polyphenolic flavonoid found in...
Autores principales: | Huang, Chun-Fa, Liu, Shing-Hwa, Ho, Tsung-Jung, Lee, Kuan-I, Fang, Kai-Min, Lo, Wu-Chia, Liu, Jui-Ming, Wu, Chin-Ching, Su, Chin-Chuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8771640/ https://www.ncbi.nlm.nih.gov/pubmed/35111247 http://dx.doi.org/10.3892/ol.2022.13198 |
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