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Dimethyl Fumarate Reduces Inflammation in Chronic Active Multiple Sclerosis Lesions

BACKGROUND AND OBJECTIVES: To determine the effects of dimethyl fumarate (DMF) and glatiramer acetate on iron content in chronic active lesions in patients with multiple sclerosis (MS) and in human microglia in vitro. METHODS: This was a retrospective observational study of 34 patients with relapsin...

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Detalles Bibliográficos
Autores principales: Zinger, Nicole, Ponath, Gerald, Sweeney, Elizabeth, Nguyen, Thanh D., Lo, Chih Hung, Diaz, Ivan, Dimov, Alexey, Teng, Leilei, Zexter, Lily, Comunale, Joseph, Wang, Yi, Pitt, David, Gauthier, Susan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8771666/
https://www.ncbi.nlm.nih.gov/pubmed/35046083
http://dx.doi.org/10.1212/NXI.0000000000001138