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Marine Depsipeptide Nobilamide I Inhibits Cancer Cell Motility and Tumorigenicity via Suppressing Epithelial–Mesenchymal Transition and MMP2/9 Expression

[Image: see text] A cyclic depsipeptide, nobilamide I (1), along with the known peptide A-3302-B/TL-119 (2), was isolated from the saline cultivation of the marine-derived bacterium Saccharomonospora sp., strain CNQ-490. The planar structure of 1 was elucidated by interpretation of 1D and 2D NMR and...

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Detalles Bibliográficos
Autores principales: Le, Tu Cam, Pulat, Sultan, Lee, Jihye, Kim, Geum Jin, Kim, Haerin, Lee, Eun-Young, Hillman, Prima F., Choi, Hyukjae, Yang, Inho, Oh, Dong-Chan, Kim, Hangun, Nam, Sang-Jip, Fenical, William
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8771697/
https://www.ncbi.nlm.nih.gov/pubmed/35071867
http://dx.doi.org/10.1021/acsomega.1c04520