12/15-Lipoxygenase Deficiency Impairs Neutrophil Granulopoiesis and Lung Proinflammatory Responses to Aspergillus fumigatus

Development of invasive aspergillosis correlates with impairments in innate immunity. We and others have recently shown that arachidonic acid metabolism pathways, specifically the cyclooxygenase-2 (COX-2) and 5-lipoxygenase (5-LOX) pathways, participate in the induction of protective innate immune r...

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Detalles Bibliográficos
Autores principales: Mackel, Joseph J., Garth, Jaleesa M., Blackburn, Jonathan P., Jones, MaryJane, Steele, Chad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8771824/
https://www.ncbi.nlm.nih.gov/pubmed/32102903
http://dx.doi.org/10.4049/jimmunol.1900808

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8771824/
https://www.ncbi.nlm.nih.gov/pubmed/32102903
http://dx.doi.org/10.4049/jimmunol.1900808

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