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Diverse Ras-related GTPase DIRAS2, downregulated by PSMD2 in a proteasome-mediated way, inhibits colorectal cancer proliferation by blocking NF-κB signaling

Colorectal cancer (CRC) is the most common gastrointestinal cancer, with a high mortality rate but limited therapeutic targets. DIRAS family GTPase 2 (DIRAS2) is a member of the Ras-related small G-protein family whose biological functions and underlying mechanism in CRC remain poorly understood. In...

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Detalles Bibliográficos
Autores principales: Ying, Ke, Wang, Chan, Liu, Shuiping, Kuang, Yeye, Tao, Qian, Hu, Xiaotong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8771839/
https://www.ncbi.nlm.nih.gov/pubmed/35173535
http://dx.doi.org/10.7150/ijbs.68312