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A Sonic Hedgehog-Gli-Bmi1 signaling pathway plays a critical role in p27 deficiency induced bone anabolism

To explore the mechanism of the bone anabolic action of p27 deficiency, we first confirmed that osteoblast formation and osteogenesis were significantly increased in p27 deficient mice compared with their wild-type littermates. Microarray analysis of differential gene expression profiles, followed b...

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Detalles Bibliográficos
Autores principales: Wu, Jun, Wang, Rong, Kan, Xuechun, Zhang, Jinghan, Sun, Wen, Goltzman, David, Miao, Dengshun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8771843/
https://www.ncbi.nlm.nih.gov/pubmed/35173529
http://dx.doi.org/10.7150/ijbs.65954