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Ascorbic acid induced TET2 enzyme activation enhances cancer immunotherapy efficacy in renal cell carcinoma

Exploring the regulatory mechanism of PD-L1 in renal cancer is one of the key strategies to improve the response of renal cancer patients to checkpoint blockade therapy. In this study, the synergistic effect of ascorbic acid (vitamin C) supplementation and the impact of TET2 depletion on anti-PD-L1...

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Detalles Bibliográficos
Autores principales: Peng, Ding, He, Anbang, He, Shiming, Ge, Guangzhe, Wang, Shuo, Ci, Weimin, Li, Xuesong, Xia, Dan, Zhou, Liqun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8771844/
https://www.ncbi.nlm.nih.gov/pubmed/35173532
http://dx.doi.org/10.7150/ijbs.67329