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VRK2 activates TNFα/NF-κB signaling by phosphorylating IKKβ in pancreatic cancer

NF-κB signaling is active in more than 50% of patients with pancreatic cancer and plays an important role in promoting the progression of pancreatic cancer. Revealing the activation mechanism of NF-κB signaling is important for the treatment of pancreatic cancer. In this study, the regulation of TNF...

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Detalles Bibliográficos
Autores principales: Chen, Jionghuang, Qiao, Kexiong, Zhang, Chaolei, Zhou, Xinyang, Du, Qian, Deng, Yuezhen, Cao, Liping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8771851/
https://www.ncbi.nlm.nih.gov/pubmed/35173553
http://dx.doi.org/10.7150/ijbs.66313