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Hypoxic pancreatic cancer derived exosomal miR-30b-5p promotes tumor angiogenesis by inhibiting GJA1 expression

Purpose: Most patients with pancreatic ductal adenocarcinoma (PDAC) have vascular invasion and metastasis, leading to low surgical resection rate and dismal prognosis. Tumor angiogenesis is related to vascular invasion and metastasis. However, anti-angiogenesis therapeutic effects in PDAC are limite...

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Detalles Bibliográficos
Autores principales: Chen, Kai, Wang, Qi, Liu, Xinxin, Wang, Feng, Yang, Yinmo, Tian, Xiaodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8771853/
https://www.ncbi.nlm.nih.gov/pubmed/35173549
http://dx.doi.org/10.7150/ijbs.67675