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CXCR4-dependent macrophage-to-fibroblast signaling contributes to cardiac diastolic dysfunction in heart failure with preserved ejection fraction

Rationale: Heart failure with preserved ejection fraction (HFpEF) can arise from hypertension‐induced cardiac remodeling. Monocyte/macrophage accumulation and inflammation are crucial elements in the pathogenesis of hypertension-induced cardiac remodeling. The C-X-C chemokine receptor 4 (CXCR4) is a...

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Detalles Bibliográficos
Autores principales: Zhang, Ning, Ma, Qunchao, You, Yayu, Xia, Xiangyang, Xie, Cuiping, Huang, Yuxue, Wang, Zhuo, Ye, Feiming, Yu, Zhaosheng, Xie, Xiaojie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8771855/
https://www.ncbi.nlm.nih.gov/pubmed/35173552
http://dx.doi.org/10.7150/ijbs.65802