Highly Sensitive Fluorescence Assay for miRNA Detection: Investigation of the DNA Spacer Effect on the DSN Enzyme Activity toward Magnetic-Bead-Tethered Probes

[Image: see text] Researchers have recently designed various biosensors combining magnetic beads (MBs) and duplex-specific nuclease (DSN) enzyme to detect miRNAs. Yet, the interfacial mechanisms for surface-based hybridization and DSN-assisted target recycling are relatively not well understood. Thu...

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Detalles Bibliográficos
Autores principales: Djebbi, Khouloud, Shi, Biao, Weng, Ting, Bahri, Mohamed, Elaguech, Mohamed Amin, Liu, Jin, Tlili, Chaker, Wang, Deqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8771974/
https://www.ncbi.nlm.nih.gov/pubmed/35071911
http://dx.doi.org/10.1021/acsomega.1c05775

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8771974/
https://www.ncbi.nlm.nih.gov/pubmed/35071911
http://dx.doi.org/10.1021/acsomega.1c05775

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