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Allosteric perspective on the mutability and druggability of the SARS-CoV-2 Spike protein

Recent developments in the SARS-CoV-2 pandemic point to its inevitable transformation into an endemic disease, urging both refinement of diagnostics for emerging variants of concern (VOCs) and design of variant-specific drugs in addition to vaccine adjustments. Exploring the structure and dynamics o...

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Detalles Bibliográficos
Autores principales: Tan, Zhen Wah, Tee, Wei-Ven, Samsudin, Firdaus, Guarnera, Enrico, Bond, Peter J., Berezovsky, Igor N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8772014/
https://www.ncbi.nlm.nih.gov/pubmed/35063064
http://dx.doi.org/10.1016/j.str.2021.12.011