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Allosteric perspective on the mutability and druggability of the SARS-CoV-2 Spike protein
Recent developments in the SARS-CoV-2 pandemic point to its inevitable transformation into an endemic disease, urging both refinement of diagnostics for emerging variants of concern (VOCs) and design of variant-specific drugs in addition to vaccine adjustments. Exploring the structure and dynamics o...
Autores principales: | Tan, Zhen Wah, Tee, Wei-Ven, Samsudin, Firdaus, Guarnera, Enrico, Bond, Peter J., Berezovsky, Igor N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Ltd.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8772014/ https://www.ncbi.nlm.nih.gov/pubmed/35063064 http://dx.doi.org/10.1016/j.str.2021.12.011 |
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