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MicroRNA-377-3p inhibits hepatocellular carcinoma growth and metastasis through negative regulation of CPT1C-mediated fatty acid oxidation

BACKGROUND: Altered lipid metabolism is closely related to the occurrence and development of hepatocellular carcinoma (HCC). Carnitine palmitoyltransferase 1C (CPT1C) is a member of CPT1 family and plays a key role in cancer development and progression. However, how microRNAs (miRNAs) regulate CPT1C...

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Detalles Bibliográficos
Autores principales: Zhang, Ting, Zhang, Yanan, Liu, Jie, Ma, Yan, Ye, Qinong, Yan, Xinlong, Ding, Lihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8772112/
https://www.ncbi.nlm.nih.gov/pubmed/35057851
http://dx.doi.org/10.1186/s40170-021-00276-3