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Mechanisms of flecainide induced negative inotropy: An in silico study

It is imperative to develop better approaches to predict how antiarrhythmic drugs with multiple interactions and targets may alter the overall electrical and/or mechanical function of the heart. Safety Pharmacology studies have provided new insights into the multi-target effects of many different cl...

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Detalles Bibliográficos
Autores principales: Yang, Pei-Chi, Giles, Wayne R., Belardinelli, Luiz, Clancy, Colleen E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8772296/
https://www.ncbi.nlm.nih.gov/pubmed/34004185
http://dx.doi.org/10.1016/j.yjmcc.2021.05.007