Polyhydroxylated Cyclopentane β-Amino Acids Derived from d-Mannose and d-Galactose: Synthesis and Protocol for Incorporation into Peptides

[Image: see text] A stereoselective synthesis of polyhydroxylated cyclopentane β-amino acids from hexoses is reported. The reaction sequence comprises, as key steps, ring-closing metathesis of a polysubstituted diene intermediate followed by the stereoselective aza-Michael functionalization of the r...

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Detalles Bibliográficos
Autores principales: Fernández, Fernando, Fernández, Alberto G., Balo, Rosalino, Sánchez-Pedregal, Víctor M., Royo, Miriam, Soengas, Raquel G., Estévez, Ramón J., Estévez, Juan C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8772316/
https://www.ncbi.nlm.nih.gov/pubmed/35071888
http://dx.doi.org/10.1021/acsomega.1c05468

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8772316/
https://www.ncbi.nlm.nih.gov/pubmed/35071888
http://dx.doi.org/10.1021/acsomega.1c05468

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