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Polyhydroxylated Cyclopentane β-Amino Acids Derived from d-Mannose and d-Galactose: Synthesis and Protocol for Incorporation into Peptides
[Image: see text] A stereoselective synthesis of polyhydroxylated cyclopentane β-amino acids from hexoses is reported. The reaction sequence comprises, as key steps, ring-closing metathesis of a polysubstituted diene intermediate followed by the stereoselective aza-Michael functionalization of the r...
Autores principales: | Fernández, Fernando, Fernández, Alberto G., Balo, Rosalino, Sánchez-Pedregal, Víctor M., Royo, Miriam, Soengas, Raquel G., Estévez, Ramón J., Estévez, Juan C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8772316/ https://www.ncbi.nlm.nih.gov/pubmed/35071888 http://dx.doi.org/10.1021/acsomega.1c05468 |
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